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Penicillin - the true story?

Imagine - if you had been born more than about sixty five years ago and got a throat infection or a scratch that went septic, you would quite possibly have died. The discovery of penicillin, and the production of the drug on a large scale which meant that bacterial diseases could easily be cured, seemed like a miracle. We still reap the benefits of this amazing drug today.

disease
Victims of bubonic plague in the Middle Ages. Without modern antibiotics, plague is fatal in up to 75% of cases.

The popular story of how penicillin was discovered is well known. The Scottish scientist Alexander Fleming was working on bacteria in the labs of St Mary's Hospital, London. He went away on holiday leaving some agar plates exposed on a lab bench near a windowsill. When he came back he noticed that there were small colonies of mould growing on his plates - and that around the colonies of mould were clear areas where the bacteria which covered the rest of the plate were not growing. Fleming realised that the mould must be making a chemical which killed the bacteria, and so penicillin was discovered.

  • Just how accurate is this story?
  • Was it really just sheer chance that Fleming made his discovery?
  • What scientific ideas needed to be in place before penicillin could be discovered?
  • When Fleming was awarded the Nobel prize for the discovery of penicillin, two other scientists shared the prize for their work on penicillin. Who were they are and what did they do?
  • Did anyone else play a part in the penicillin story?

To find these answers to these and other questions click on the links below :

resource ... The germ theory of disease

resource ... Finding out about Fleming

resource ... Florey, Chain and large-scale production

resource ... Accident or design?

resource ... The unsung heroes

 
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