| 1504 |
Christopher Columbus correctly
predicts the total eclipse of the moon. |
| 1517 |
Girolamo Francastoro explains
fossils as the remains of actual organisms - he decides that
there are too many to be simply the result of Noah's flood. |
| 1518 - 25 |
Smallpox reaches the Americas
and causes huge loss of life among the native population. |
| 1520 |
The Swiss doctor and alchemist
Philippus Aureolus Paracheus introduces laudanum (made
from opium) as a pain killer. |
| 1540 |
The book Astronomicon Caesareum
by Peter Apian notes that the tails of comets point
away from the Sun, a fact known by the Chinese since 635 AD.
|
| 1543 |
The astronomer Nicholas Copernicus publishes his
book De revolutionibus orbium coelestium ("On
the revolutions of the heavenly bodies") which describes
how the Earth and other planets orbit around the Sun. This
theory is to replace earlier ideas that the Earth is fixed
at the centre of the Universe, but it will be many years
until this theory is accepted by more than a few people
- the Catholic church will officially deny Copernicus's
ideas until 1922.
In the same year the physician Andreas Vesalius
also publishes a book. De humani corporis fabrica
("On the structure of the human body") is important
because Vesalius has obtained his ideas about anatomy through
observing human bodies as they are cut up. Up until this
point anatomists have based all their ideas on the written
works of the Roman physician Galen, who lived and worked
in the second century AD in an area of the world that is
now part of Turkey. 
|
| 1545 |
A book on surgery by the French
author Ambroise Paré suggests treating wounds
with soothing ointments instead of boiling oil. |
| 1546 |
Girolamo Fracastoro puts
forward the idea that diseases are like seeds that can be
transferred from one person to another. |
| 1552 |
The Italian anatomist Bartolemeo Eustachio discovers
the adrenal glands, the detailed structure of the teeth
and the Eustachian tubes which were named after him, although
he did not publish his work until 1711.
Late January/early February in Shensi Province of China
- the worst earthquake ever kills 830,000 people.
|
| 1557 |
The first mention
of the metal platinum in any written text. |
| 1560 |
An Italian physicist forms the
first scientific society. This is suppressed by the Inquisition. |
| 1565 |
The first known drawings of fossils
are published. Konrad von Gesner, the artist who did
them, thinks they are tools that look like bones or shells.
|
| 1570 |
The pinhole camera is invented
around this time. |
| 1579 |
The first glass eyes are made. |
| 1581 |
Galileo uses his pulse
to time the swinging of the lamps in the cathedral at Pisa.
He concludes that the time for a lamp to swing does not depend
on the angle through which it swings. This observation eventually
leads to the development of pendulum clocks. |
| 1591 |
Thomas Harriot, an English
mathematician, first notes snowflakes are six pointed or six
sided although he does not publish this observation. The hexagonal
character of snowflakes has been known in China from at least
the 2nd century BC. |
| 1592 |
Galileo develops a type
of thermometer based on air. |
| 1597 |
Galileo accepts the ideas of Copernicus about the
Solar System.
Andreas Libavius publishes Alchemia. This
chemistry textbook describes how to make hydrochloric acid
and ammonium sulphate and other chemicals.
|
| 1599 |
The first serious textbook of
zoology is published by Ulisse Aldrovandi. |